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In-Depth Scientific Insights

Sagol Center for Hyperbaric Medicine and Research, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel

HBOT improves dysexecutive functions, psychiatric symptoms (depression, anxiety and somatization), pain interference symptoms and fatigue. Those changes were associated with increased CBF and brain microstructural changes in frontal, parietal and limbic regions associated with cognitive and psychiatric roles.

Research and Development Unit, Shamir Medical Center, Zerifin, Israel

The study indicates that HBOT can induce significant senolytic effects, including significant increased telomere length and clearance of senescent cells in aging populations.

National Center for Biotechnology Information

Several clinical studies have been conducted to evaluate the influence of HBOT on neurodegenerative diseases, and of other neurological conditions like stroke and traumatic brain injury which predisposes patients to developing neurodegenerative diseases like AD

Proven Benefits of HBOT: Science-Backed Insights into Hyperbaric Oxygen Therapy

Backed by extensive research, this therapy has been shown to support faster recovery from injuries, improve cognitive function, and aid in the management of chronic conditions. Our comprehensive overview delves into the robust scientific evidence that highlights how HBOT can rejuvenate your health and enhance your overall well-being, offering a powerful tool for those seeking evidence-b

Stimulated Stem Cell Growth

Promotes the proliferation and differentiation of stem cells, which can aid in tissue regeneration and repair, supporting overall healing processes.

Support for Chronic Conditions

Aids in the management of various chronic conditions, including diabetic ulcers and radiation damage, by improving oxygen delivery and tissue health.

Enhanced Athletic Recovery

Speeds up muscle recovery and reduces fatigue after intense physical exertion, helping athletes return to peak performance faster.

Improved Cognitive Function

Enhances brain oxygenation, potentially supporting better cognitive performance and mental clarity.

Accelerated Wound Healing

Boosts oxygen supply to damaged tissues, speeding up recovery and reducing healing times for wounds and injuries.

Increased Energy Levels

Boosts overall energy by improving cellular metabolism and reducing oxidative stress, leading to enhanced vitality and stamina.

Research and Publications

Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial”
Outcome: This study demonstrated that 60 HBOT sessions significantly increased telomere length in various immune cells (T-helper, T-cytotoxic, natural killer, and B cells) by over 20%. It also showed a reduction in senescent cells, particularly a decrease of 37.3% in T-helper senescent cells.
Publisher: Aging-US
Date: 2020
Link: https://pubmed.ncbi.nlm.nih.gov/33206062/

The effect of hyperbaric oxygen therapy on the pathophysiology of skin aging: a prospective clinical trial
Outcome: The research showed that 60 sessions of HBOT decreased papillary dermis thickness, increased elastic fiber length and collagen density, and led to a significant increase in the number of blood vessels while decreasing senescent cells in the skin.
Publisher: Aging-US
Date: 2021
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660605/

Hyperbaric Oxygen Therapy Improves Cognitive Function in Post-Stroke Patients
Outcome: HBOT significantly improves cognitive function and reduces neurological deficits in patients recovering from stroke.
Link: https://pubmed.ncbi.nlm.nih.gov/31985478/
Publisher: National Library of Medicine – National Institutes of Health U.S.

Hyperbaric Oxygen Treatment—From Mechanisms to Cognitive Improvement
Outcome: Comprehensive review of HBOT’s mechanisms and its effectiveness in improving cognitive function across various conditions.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533945/
Publisher: National Library of Medicine – National Institutes of Health U.S.

Hyperbaric Oxygen Therapy in the Treatment of Autism: A Pilot Study
Outcome: HBOT improves social interaction, communication, and behavioral outcomes in children with autism spectrum disorder.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471082/
Publisher: National Library of Medicine – National Institutes of Health U.S.

Hyperbaric Oxygen Therapy Enhances the Effectiveness of Cancer Treatment
Outcome: HBOT enhances the sensitivity of cancer cells to radiotherapy and chemotherapy, potentially improving treatment outcomes.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510426/
Publisher: National Library of Medicine – National Institutes of Health U.S.

Hyperbaric Oxygen Therapy for Ischemia-Reperfusion Injury in Organ Transplantation
Outcome: HBOT reduces ischemia-reperfusion injury, promoting better organ recovery and function after transplantation.
Link: https://www.ncbi.nlm.nih.gov/books/NBK513221/
Publisher: National Library of Medicine – National Institutes of Health U.S.

Hyperbaric Oxygen Therapy as a Potential Treatment for Alzheimer’s Disease
Outcome: HBOT shows promise in improving cognitive function and reducing neuroinflammation in patients with Alzheimer’s disease.
Link: https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2024.1360148/full
Publisher: Frontiers in Aging Neuroscience

The U.S. Food and Drug Administration (FDA) has approved hyperbaric oxygen therapy to help treat the following conditions
Outcome: Overview of FDA-approved uses of HBOT, including the treatment of wounds, infections, and decompression sickness.
Link: https://my.clevelandclinic.org/health/treatments/17811-hyperbaric-oxygen-therapy
Publisher: Cleveland Clinic, a non-profit academic medical center, provides clinical and hospital care and is a leader in research, education and health information.

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Hyperbaric Oxygen Treatment: A Novel Therapeutic Approach for Neurodegenerative Disorders
Outcome: Explores the potential of HBOT in treating neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases.
Link: https://www.sciencedirect.com/science/article/pii/S2213231722001240
Publisher: ScienceDirect, world’s leading source for scientific, technical, and medical research

Hyperbaric Oxygen Therapy as an Adjunctive Treatment for Radiation-Induced Tissue Damage
Outcome: HBOT reduces tissue damage and promotes healing in patients with radiation-induced injuries, such as osteoradionecrosis.
Link: https://pubmed.ncbi.nlm.nih.gov/24089098/
Publisher: National Library of Medicine – National Institutes of Health U.S

Overview of Hyperbaric Oxygen Therapy from Johns Hopkins Medicine
Outcome: Provides a general overview of HBOT, its mechanisms, and its applications in modern medicine.
Link:https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/hyperbaric-oxygen-therapy
Publisher: Johns Hopkins Medicine, a leading health system and academic institution in the U.S.

Hyperbaric Oxygen Therapy Promotes Wound Healing in Diabetic Foot Ulcers
Outcome: HBOT enhances the healing process of chronic diabetic foot ulcers, leading to faster recovery and reduced need for amputations.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858192/
Publisher: National Library of Medicine – National Institutes of Health

The Role of Hyperbaric Oxygen Therapy in Traumatic Brain Injury Recovery
Outcome: HBOT improves neuroplasticity and cognitive outcomes in patients with traumatic brain injury, aiding in long-term recovery.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110132/

Publisher: National Library of Medicine – National Institutes of Health U.S.

Efficacy of Hyperbaric Oxygen Therapy in Enhancing Stem Cell Mobilization
Outcome: HBOT effectively increases the mobilization of stem cells, supporting regenerative processes and tissue repair.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318163/
Publisher: National Library of Medicine – National Institutes of Health U.S.

Hyperbaric Oxygen Therapy Improves Motor Function in Cerebral Palsy
Outcome: HBOT leads to significant improvements in motor function and quality of life in children with cerebral palsy.
Link:https://www.cerebralpalsyguidance.com/cerebral-palsy/treatment/hyperbaric-oxygen-therapy/
Publisher: Cerebral Palsy Guide, a U.S. support organization that provides information and resources to individuals and families affected by cerebral palsy.

Hyperbaric Oxygen Therapy Increases Telomere Length and Decreases Immunosenescence in Humans
Outcome: HBOT shows anti-aging effects by increasing telomere length and reducing immunosenescence, which are key markers of aging.
Link: https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2024.1368982/full
Publisher: Frontiers in Aging

Hyperbaric Oxygen Therapy Enhances Stem Cell Proliferation and Tissue Regeneration
Outcome: HBOT significantly enhances stem cell proliferation, leading to improved tissue regeneration and repair.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775938/
Publisher: National Library of Medicine – National Institutes of Health U.S.